The September 30, 2005 Edition of Smackdown is a Professional wrestling television show of the WWE's Smackdown brand, which took take place on September 27, 2005 at the Laredo Entertainment Center in Laredo, Texas.
- Numbers in parentheses indicate the length of the match.
- (c) refers to the champion(s) heading into the match.
- John Bradshaw Layfield & Ken Kennedy defeated Hardcore Holly & Rey Mysterio (7:46)
- Melina (w/ Mercury & Nitro) defeated Christy Hemme (4:45)
- The Undertaker defeated Bob Orton, Jr. (5:06)
- Bobby Lashley defeated Russell Simpson (2:20)
- Orlando Jordan defeated Booker T and Christian in a Triple Threat Match (4:30)
- The Legion of Doom (Heidenreich & Road Warrior Animal) (c) defeated Batista & Eddie Guerrero by DQ to retain the WWE Tag Team Championship (5:15)