The September 23, 2005 Edition of Smackdown is a Professional wrestling television show of the WWE's Smackdown brand, which took take place on September 20, 2005 at the United Spirit Arena in Lubbock, Texas.
- Numbers in parentheses indicate the length of the match.
- (c) refers to the champion(s) heading into the match.
- Booker T (w/ Sharmell) defeated Christian (9:26)
- The Legion of Doom (Heidenreich & Road Warrior Animal) (c) defeated Anthony Colletti & Jared Steele (1:01)
- Hardcore Holly defeated Sylvan by Count Out (4:28)
- Ken Kennedy defeated Rey Mysterio (5:20)
- Bobby Lashley defeated Simon Dean (2:46)
- Chris Benoit (c) defeated Orlando Jordan to retain the WWE United States Championship (0:50)
- Batista & Eddie Guerrero defeated MNM (Mercury & Nitro) (w/ Melina) (6:02)