The September 22, 1991 edition of Wrestling Challenge is a Professional wrestling television show of the World Wrestling Federation. It was taped on August 20, 1991 at the Erie Civic Center in Erie, Pennsylvania.
- Numbers in parentheses indicate the length of the match.
- (c) refers to the champion(s) heading into the match.
- Virgil defeated Bubba Monroe
- The Berzerker (w/ Mr. Fuji) defeated Ron Cumberledge by Count Out
- The Mountie (w/ Jimmy Hart) defeated Tony Diamond
- Jim Neidhart defeated Duane Gill
- The Texas Tornado defeated Barry Hardy
- The Undertaker (w/ Paul Bearer) defeated Chris Hahn