The September 16, 2010 Edition of TNA iMPACT! is a Professional wrestling television show of Total Nonstop Action Wrestling. It was taped on September 6, 2010 in the TNA Impact Zone in Orlando, Florida.
- Numbers in parentheses indicate the length of the match.
- (c) refers to the champion(s) heading into the match.
- Kevin Nash (w/ Sting) vs. Samoa Joe (w/ Jeff Jarrett) ended in a double Countout (2:39)
- Jay Lethal defeated Douglas Williams (c) to win the TNA X-Division Championship (5:12)
- Hamada & Taylor Wilde (c) defeated Lacey Von Erich & Madison Rayne (w/ Tara) to retain the TNA Women's Knockout Championship (4:02)
- Brian Kendrick defeated Matt Morgan (2:01)
- Jeff Hardy vs. Kurt Angle ended in a Double Pin in a TNA World Heavyweight Title Match # 1 Contendership (21:41)