Bitter Friends, Stiffer Enemies 2 featured professional wrestling matches, which involved different wrestlers from pre-existing scripted feuds, plots, and storylines that played out on ROH's television programs. Wrestlers portrayed villains or heroes as they followed a series of events that built tension and culminated in a wrestling match or series of matches.
- Numbers in parentheses indicate the length of the match.
- (c) refers to the champion(s) heading into the match.
- Dark match: The Hybrids (Donovan Cain & Jayson Lyte) defeated Zero Gravity (Brett Gakiya & CJ Esparza)
- Dark match: ??? vs. Kyle O'Reilly ended in a No Contest
- Dark match: Prince Mustafa Ali won a Battle Royal
- Rasche Brown defeated Sami Callihan (6:41)
- The Dark City Fight Club (Jon Davis & Kory Chavis) defeated The Bravado Brothers (Harlem Bravado & Lance Bravado) (5:42)
- Eddie Edwards defeated The Metal Master (10:50)
- The Embassy (Erick Stevens & Shawn Daivari) defeated The House Of Truth (Christin Able & Josh Raymond) (w/ Truth Martini) by DQ (13:22)
- Davey Richards vs. Roderick Strong ended in a Time Limit Draw (20:29)
- Rhett Titus defeated Petey Williams (12:10)
- The Briscoes (Jay Briscoe & Mark Briscoe) defeated Austin Aries & Kenny King (14:20)
- Tyler Black (c) defeated Chris Hero to retain the ROH World Championship (24:05)
- Colt Cabana & El Generico defeated Kevin Steen & Steve Corino in a Chicago Street Fight (20:00)
|2010 Ring of Honor Events|
SoCal Showdown • 8th Anniversary Show • Gold Rush • Epic Encounter III • From The Ashes • Phoenix Rising • The Big Bang! • Pick Your Poison • Bitter Friends, Stiffer Enemies 2 • Civil Warfare • Supercard of Honor V • Buffalo Stampede II • Death Before Dishonor VIII • The Bluegrass Brawl • Hate: Chapter II • Salvation • Champions Challenge • Tag Wars 2010 • Fade To Black • Glory by Honor IX • Allied Forces • Richards Vs. Daniels • Survival Of The Fittest • Fate Of An Angel II • Tag Title Classic II • Final Battle