The October 7, 1999 Edition of Smackdown! was a televised Professional wrestling event by the WWF's Smackdown! brand. It was taped on October 5, 1999 at the Nassau Coliseum in Long Island, New York. This taping was where Droz was paralyzed from the waist-down after D'Lo Brown botched a running powerbomb.
- Numbers in parentheses indicate the length of the match.
- (c) refers to the champion(s) heading into the match.
- X-Pac & Kane defeated Viscera & Mideon (2:41)
- Hardcore Holly (w/ Crash Holly) defeated Road Dogg (w/ Billy Gunn) (5:14)
- The Hardy Boyz (Jeff and Matt Hardy) defeated Edge & Christian (6:12)
- Ivory defeated Miss Kitty in a mud wrestling match.
- Mankind vs. The British Bulldog ended in a no contest (6:15)
- The Big Show defeated The Big Bossman via DQ (2:25)
- The Rock defeated Val Venis (10:14)
- Unaired match: Droz vs. D'Lo Brown ended in a no-contest after Brown botched a running powerbomb and broke Droz's neck, paralyzing him from the waist-down.