The October 4, 2001 Edition of Smackdown! was a televised Professional wrestling event by the WWF's Smackdown! brand, which took place on October 2, 2001 at the Mobile Civic Center in Mobile, Alabama.
- Numbers in parentheses indicate the length of the match.
- (c) refers to the champion(s) heading into the match.
- Six Man Tag Team Match: Edge and The APA (Bradshaw & Faarooq) defeated X-Factor (Albert & X-Pac) and Christian (4:07)
- Tag Team Match: Spike Dudley & The Big Show defeated Mike Awesome & The Hurricane (w/ Mighty Molly) (4:10)
- Non Title Match: Rob Van Dam defeated WWF Champion Kurt Angle (8:59)
- Singles Match: Tazz defeated Maven (2:00)
- Singles Match: Booker T defeated Kane (5:51)
- Six Man Tag Team Match: The Rock, Mike Chioda and Chris Jericho defeated The Dudley Boyz (Bubba Ray & D-Von Dudley) and Nick Patrick (10:36)