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The October 29, 2010 Edition of Smackdown is a Professional wrestling television show of the WWE's Smackdown brand, which took take place on October 26, 2010 at the Bradley Center in Milwaukee, Wisconsin.
- Numbers in parentheses indicate the length of the match.
- (c) refers to the champion(s) heading into the match.
- Dark Match: The Dudebusters (Caylen Croft & Trent Barreta) defeated Luke Gallows & Vance Archer
- Daniel Bryan defeated Dolph Ziggler (w/ Vickie Guerrero)
- Jack Swagger defeated Kaval
- The Bella Twins (Brie Bella & Nikki Bella), Kelly Kelly & Melina defeated LayCool (Layla & Michelle McCool), Alicia Fox & Rosa Mendes in an Eight Man Tag Team Match
- Kofi Kingston & The Big Show defeated Cody Rhodes & Drew McIntyre
- Edge defeated Alberto Del Rio & Rey Mysterio in a Triple threat match to become the World Heavyweight Title #1 Contender
- Dark Match: Edge, Rey Mysterio & The Big Show defeated Alberto Del Rio, Jack Swagger & Kane in a six man tag match