The October 21, 1990 edition of Wrestling Challenge is a Professional wrestling television show of the World Wrestling Federation. It was taped on September 19, 1990 at the IMA Sports Arena in Flint, Michigan.
- Numbers in parentheses indicate the length of the match.
- (c) refers to the champion(s) heading into the match.
- Jim Duggan defeated Gary Richards
- The Hart Foundation (Bret Hart & Jim Neidhart) (c) defeated Alan Reynolds & Randy Jackson to retain the WWF World Tag Team Championship (2:11)
- Rick Rude (w/ Bobby Heenan) defeated Jim Evans (1:06)
- Marty Jannetty defeated Paul Diamond (5:10)
- Demolition (Ax, Crush & Smash) defeated Kent Carlson, Kevin Krueger & WT Jones