The November 21, 2008 Edition of Smackdown is a Professional wrestling television show of the WWE's Smackdown brand, it was taped on November 11, 2008 at the Manchester Evening News Arena in Manchester, England.
- Numbers in parentheses indicate the length of the match.
- (c) refers to the champion(s) heading into the match.
- Smackdown #483
- [Smackdown #483 on WWE Network]