|Friday Night Smackdown|
|Date||May 5, 2006|
|Venue||US Bank Arena|
|Previous episode||April 28, 2006|
|Next episode||May 12, 2006|
- Numbers in parentheses indicate the length of the match.
- (c) refers to the champion(s) heading into the match.
- Booker T (w/ Sharmell) defeated Gunner Scott (5:29)
- MNM (Mercury & Nitro) (w/ Melina) (c) vs. Brian Kendrick & Paul London ended in a no contest to retain the WWE Tag Team Championship
- Finlay defeated Chris Benoit in a King Of The Ring 2006 First Round Match (20:24)
- The Gymini (Jake & Jesse) (w/ Simon Dean) defeated Funaki & Scotty 2 Hotty (3:27)
- Kid Kash vs. Nunzio (w/ Vito) vs. Super Crazy ended in a no contest in a WWE Cruiserweight Title #1 Contendership Match (2:00)
- Mark Henry defeated Rey Mysterio (5:18)
- Dark Match: Rey Mysterio (c) defeated John Bradshaw Layfield and Mark Henry to retain the World Heavyweight Championship
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