The May 22, 1988 edition of Wrestling Challenge is a Professional wrestling television show of the World Wrestling Federation. It was taped on May 11, 1988 at the Mayo Civic Center in Rochester, Minnesota.
- Numbers in parentheses indicate the length of the match.
- (c) refers to the champion(s) heading into the match.
- Dark match: Koko B. Ware defeated Bobby Heenan
- Jake Roberts defeated Steve Lombardi (1:32)
- Bad News Brown defeated Chris Zarna (2:37)
- The Young Stallions (Jim Powers & Paul Roma) defeated Rick Gantner & Tom Stone (3:20)
- Hercules (w/ Bobby Heenan) defeated Billy Bowman (1:53)
- The Junkyard Dog defeated Terry Gibbs (1:57)
- The Fabulous Rougeaus (Jacques Rougeau & Raymond Rougeau) defeated Dave Wagner & Rick Renslow (2:15)