The March 19, 2010 Edition of Smackdown is a Professional wrestling television show of the WWE's Smackdown brand, took place on March 16, 2010 at the Staples Center in Los Angeles, California.
- Numbers in parentheses indicate the length of the match.
- (c) refers to the champion(s) heading into the match.
Mysterio accepts Punk's Wrestlemania challenge
Swagger & Ziggler v Matt Hardy & MVP
Phoenix & Tiffany v McCool & Layla
Jericho attacks Edge
John Morrison & R-Truth v The Hart Dynasty
Luke Gallows v Rey Mysterio
Undertaker v Drew McIntyre