The July 21, 2005 Edition of Smackdown is a Professional wrestling television show of the WWE's Smackdown brand, which took take place on July 19, 2005 at the 1st Mariner Arena in Baltimore, Maryland.
- Numbers in parentheses indicate the length of the match.
- (c) refers to the champion(s) heading into the match.
- Rey Mysterio defeated Super Crazy (w/ Juventud & Psicosis) by DQ (16:59)
- Heidenreich & Road Warrior Animal defeated Julio DiNero & Nick Berk (0:31)
- Chris Benoit defeated Eddie Guerrero by Count Out (17:33)
- Booker T (w/ Sharmell) defeated Simon Dean (1:41)