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Florence is the largest city in and the county seat of Florence County, South Carolina, United States. Known as the Florence Metropolitan Statistical Area, Florence adjoins Darlington to form the core of "Pee Dee" region of South Carolina, an area that includes the eight counties of northeastern South Carolina along with sections in southeastern North Carolina. The U.S. Census Bureau estimated the city's population was 37,056 at the 2010 census. This 1997 All-America City finalist, was founded as a railroad hub city of Florence. It became the junction of three major railroad systems; the Wilmington and Manchester, The Northeastern, and the Cheraw and Darlington. Today, the city retains its status as a major hub, both for industry and infrastructure. In recent years, the city has become a regional center for business, medicine, culture and finance.

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