The February 21, 1988 edition of Wrestling Challenge is a Professional wrestling television show of the World Wrestling Federation. It was taped on January 27, 1988 at the Wicomico Youth & Civic Center in Salisbury, Maryland.
- Numbers in parentheses indicate the length of the match.
- (c) refers to the champion(s) heading into the match.
- Demolition (Ax & Smash) (w/ Mr. Fuji) defeated The Killer Bees (B. Brian Blair & Jim Brunzell) (4:08)
- The Junkyard Dog defeated Steve Lombardi (2:10)
- Dino Bravo (w/ Frenchy Martin) defeated Phil Newkirk (1:21)
- Jim Duggan defeated Terry Gibbs (1:53)
- The One Man Gang (w/ Slick) defeated Wellington Wilkins Jr. (1:57)
- Ron Bass defeated Van Van Horne (2:47)
- Dark match: The British Bulldogs (Davey Boy Smith & The Dynamite Kid) defeated The Islanders (Haku & Tama)
- Dark match: The Honky Tonk Man (w/ Jimmy Hart) (c) defeats Randy Savage to retain the WWF Intercontinental Championship
- Dark match: Bam Bam Bigelow & Hulk Hogan defeated Andre The Giant & Ted DiBiase