The August 22, 2008 Edition of Smackdown is a Professional wrestling television show of the WWE's Smackdown brand, it was taped on August 19, 2008 at the I wireless Center in Moline, Illinois.
- Numbers in parentheses indicate the length of the match.
- (c) refers to the champion(s) heading into the match.
- Armando Estrada, Curt Hawkins, Jimmy Yang, Ryan Braddock & Zack Ryder eliminated Vladimir Kozlov
- Curt Hawkins & Zack Ryder eliminated Scotty Goldman
- The Big Show eliminated Ryan Braddock
- The Big Show eliminated Curt Hawkins, Super Crazy & Zack Ryder
- The Big Show eliminated Armando Estrada
- The Big Show eliminated Funaki
- The Big Show eliminated Jimmy Wang Yang