|Friday Night Smackdown|
|Date||April 7, 2005|
|Venue||San Diego Sports Arena|
|City||San Diego, California|
|Previous episode||March 31, 2005|
|Next episode||April 14, 2005|
The April 7, 2005 Edition of Smackdown is a Professional wrestling television show of the WWE's Smackdown brand, which took take place on April 5, 2005 at the San Diego Sports Arena in San Diego, California.
- Numbers in parentheses indicate the length of the match.
- (c) refers to the champion(s) heading into the match.
- WWE Cruiserweight Title Match: Paul London (c) defeats Billy Kidman (6:14)
- Singles Match: The Big Show defeats Luther Reigns (2:13)
- Kurt Angle Invitational Challenge Match: Kurt Angle defeats Jose Macias
- WWE Heavyweight Title #1 Contendership Tournament First Round Match: John Bradshaw Layfield (w/ Orlando Jordan) defeats Rey Mysterio by DQ (15:20)
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