The April 23, 2010 Edition of Smackdown is a Professional wrestling television show of the WWE's Smackdown brand, took place on April 20, 2010 at the Mohegan Sun Arena in Uncasville, Connecticut.
- Numbers in parentheses indicate the length of the match.
- (c) refers to the champion(s) heading into the match.
John Morrison v Jack Swagger
Dolph Ziggler & Drew McIntyre defeated Matt Hardy & R-Truth
JTG v Mike Knox
Layla & Michelle McCool v Beth Phoenix and Mickie James
CM Punk & Luke Gallows v Kane & Rey Mysterio