APWA Mass Destruction 2012 took place in Shinnston, West Virginia. The event took place on July 28, 2012.
- Numbers in parentheses indicate the length of the match.
- (c) refers to the champion(s) heading into the match.
- Singles Match: Bulldozer defeats Jimmy Shane
- Tag Team Match: Team CK (Kage & Sean Carr) defeat John Greed & Tadarius Thomas
- APWA American Title Match: The Maestro defeats Joey Vengeance
- Singles Match: Santana Garrett defeats Jayme Jameson
- Three Way Match: Chris LeRusso vs. Joseph Brooks vs. Phil Atlas - No Contest
- APWA Tag Team Title #1 Contendership Three Way Match: Cash And Charisma (Chase Stevens & Christian York) defeat Joey Vengeance & Sherman Tank and Robbie E & Rob Terry
- Ten Man Tag Team Match: Team Ring Ka King (Jason Wayne, Luke Gallows, Michael Elgin, Sonjay Dutt & The Conganese Nightmare) defeat Team APWA (Chance Prophet, Crimson, Gunner, ONYX & Viper)